research: off-label use of Metformin to treat metastatic breast cancer

You may have heard about the off-label use of Metformin®, a drug prescribed for Type II diabetes, for metastatic breast cancer. This article addresses the way breast cancer uses, or steals, energy from the mitochondria of normal cells to amplify the energy to grow tumors. Researchers at the Kimmel Cancer Center at Thomas Jefferson University have shown that the process of cancer’s manipulation of the mitochondria to fuel and grow tumors can be blocked and that Metformin is effective in blocking that action.

New ‘Achilles’ heel’ in breast cancer: Tumor cell mitochondria

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© 2004–2011 Donna Peach. All rights reserved.

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